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Lang QT-tid-syndrom

Lang QT-tid-syndrom (LQTS) er en forstyrrelse i hjertets elektriske system. Tilstanden kan arte seg som uforklarlig svimmelhet, besvimelser eller plutselig død hos ellers friske, unge personer.

Lang QT-tid-syndrom er i de fleste tilfeller en arvelig tilstand, og det kan derfor være familiær opphopning av tilstanden.

Sist oppdatert:

31. mai 2023

Dette dokumentet er basert på det profesjonelle dokumentet Lang QT-tid-syndrom . Referanselisten for dette dokumentet vises nedenfor

  1. Berul CI. Acquired long QT syndrome: Definitions, causes, and pathophysiology. UpToDate, last updated Nov 06, 2020. UpToDate
  2. Schwartz PJ, Ackerman MJ. Congenital long QT syndrome: Epidemiology and clinical manifestations. UpToDate, last updated May 23, 2019. UpToDate
  3. Berul CI. Acquired long QT syndrome: Clinical manifestations, diagnosis, and management. UpToDate, last updated Feb 04, 2021. UpToDate
  4. Thorsen PJ, Berg A, Hoff PI, Greve G. Risikofaktor for brå hjertedød ved lang QT-syndrom. Tidsskr Nor Lægeforen 2006; 126: 2515-9. PubMed
  5. Arnestad M, Crotti L, Rognum et al. Prevalence of Long-QT syndrome gene variations in sudden infant death syndrome. Circulation 2007; 115: 361-7. Circulation
  6. Hermann Haugaa K, Berge KE, Früh A, et al. Kardiale kanalopatier - diagnostikk og behandling. Tidsskr Nor Lægeforen 2005; 125: 2778-81. PubMed
  7. Schwartz PJ, Ackerman MJ, Antzelevitch C, et al. Inherited cardiac arrhythmias. Nat Rev Dis Primers. 2020;6(1):58. Published 2020 Jul 16. PMID: 32678103 PubMed
  8. Berge KE, Haugaa KH, Früh A, et al. Molecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers. Scand J Clin Lab Invest 2008; 68: 362-8. PubMed
  9. Jiang R Cheung CC, Garcia-Montero M, et al. Deep Learning–Augmented ECG Analysis for Screening and Genotype Prediction of Congenital Long QT Syndrome. JAMA Cardiol 2024; 9: 377-384. pmid:38446445 PubMed
  10. Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Developed by the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC) Endorsed by the Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J 2022; 43: 3997-4126. doi:10.1093/eurheartj/ehac262 DOI
  11. Jervell A, Lange-Nielsen F. Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval and sudden death. Am Heart J 1957; 54: 59-68. PubMed
  12. Lehtonen A, Fodstad, Laitinen-Forsblom P et al. Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes. Heart Rhythm 2007; 4: 603-7. PubMed
  13. Wang C-L, Wu VC-C, Lee CH, et al. Incidences, risk factors, and clinical correlates of severe QT prolongation after the use of quetiapine or haloperidol. Heart Rhythm 2023; 24: 1547. pmid:38231170 PubMed
  14. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992; 20: 1391-6. PubMed
  15. Narayan SM. T-wave alternans and the susceptibility to ventricular arrhythmias. J Am Coll Cardiol 2006; 47: 269-81..
  16. Bundgaard H, Christiansen M, Skytt Andersen P, Kjærulf Jensen H, Hastrup Svendsen J, Kjeldsen KP. Lang QT-syndrom - gener, mekanismer og risici. Ugeskr Læger 2006; 168: 2537-42. PubMed
  17. Hamang A, Solberg B, Bjorvatn C, Greve G, Øyen N. Genetic counseling in congenital long QT syndrome. Tidsskr Nor Legeforen 2009; 129: 1226-9. Tidsskrift for Den norske legeforening
  18. Schwartz PJ, Crotti L, Insolia R. Long-QT syndrome: from genetics to management published correction appears in Circ Arrhythm Electrophysiol. 2012 Dec;5(6):e119-20. Circ Arrhythm Electrophysiol. 2012;5(4):868-877. PMID: 22895603 PubMed
  19. Tisdale JE. Drug-induced QT interval prolongation and torsades de pointes: Role of the pharmacist in risk assessment, prevention and management. Can Pharm J (Ott). 2016;149(3):139-152. PMID: 27212965 PubMed
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