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Urinsyregikt

Urinsyregikt er en betennelse i vanligvis ett ledd. Leddet blir smertefullt, varmt, rødt og hovent. Urinsyregikt blir også kalt podagra, Kaptein Vom's sykdom, og krystall-leddgikt. Forebyggende behandling anbefales.

Urinsyregikt rammer oftest stortåa, men også ankelledd, kneledd eller albueledd kan bli betente.

Sist oppdatert:

8. aug. 2023

Dette dokumentet er basert på det profesjonelle dokumentet Urinsyregikt . Referanselisten for dette dokumentet vises nedenfor

  1. Hui M, Carr A, Cameron S, et al. The British Society for Rheumatology Guideline for the management of gout. Rheumatology 2017; 56: e1–e20. doi.org
  2. Uhlig T, Halsan Liff M, Brække Norheim K, et al. Urinsyregikt (Arthritis urica). Veileder om urinsyregikt, Norsk Revmatologisk Forening, 07.09.2022. metodebok.no
  3. Bursill D, Taylor WJ, Terkeltaub R, et al. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout. Ann Rheum Dis. 2019 Nov;78(11):1592-1600. Epub 2019 Sep 9. PMID: 31501138. PubMed
  4. Clebak KT, Morrison A Croad JR. Gout: Rapid Evidence Review. Am Fam Physician 2020 Nov 1;102(9):533-538. PubMed
  5. Kapetanovic MC, Hameed M, Turkiewicz A, et al. Prevalence and incidence of gout in southern Sweden from the socioeconomic perspective. RMD Open. 2016 Nov 1;2(2):e000326. PMID: 27933209. PubMed
  6. Singh JA, Reddy SG, Kundukulam J. Risk factors for gout and prevention: a systematic review of the literature. Curr Opin Rheumatol. 2011;23(2):192–202. PMID: 21285714. PubMed
  7. Kuo CF, Grainge MJ, Mallen C, et al. Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Ann Rheum Dis. 2015;74(4):661–667. PMID: 24431399. PubMed
  8. Choi HK, Willett W, Curhan G. Fructose-rich beverages and risk of gout in women. JAMA 2010; 304: 2270-8. pmid: 21068145 PubMed
  9. Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castaneda J, et al. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79(1):31-8. PubMed
  10. Richette P, Doherty M, Pascual E, et al. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis 2019 PMID: 31167758 PubMed
  11. Janssens HJ, Fransen J, van de Lisdonk EH, et al. A diagnostic rule for acute gouty arthritis in primary care without joint fluid analysis. Arch Intern Med 2010; 170: 1120-6. pmid:20625017 PubMed
  12. Uhlig T, Eskild T, Hammer HB. Urinsyregikt – nytt innen diagnostikk og behandling. Tidsskr Nor Lægeforen 2016; 136: 1804-7. doi:10.4045/tidsskr.16.0147 DOI
  13. Dalbeth N, Kalluru R, Aati O, et al. Tendon involvment in the feet of patients with gout: a dual-energy CT study. Ann Rheum Dis 2013; 72: 1545-8. pmid: 23334212 PubMed
  14. Gaffo AL. Clinical manifestations and diagnosis of gout. UpToDate, last updated May 19, 2023. UpToDate
  15. Qaseem A, McLean RM, Starkey M, et al. Diagnosis of acute gout: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2017;166(1):52–57. PMID: 27802479.
  16. van Durme CM, Wechalekar MD, Buchbinder R, et al. Non-steroidal anti-inflammatory drugs for acute gout. Cochrane Database Syst Rev 2014; 9: CD010120. pmid:25225849 PubMed
  17. Roddy E, Clarkson K, Blagojevic-Bucknall M, et al. Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Ann Rheum Dis. 2019. PMID: 31666237 PubMed
  18. Bongartz T, Glazebrook KN, Kavros SJ, et al. Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. Ann Rheum Dis 2014. pmid: 24671771 PubMed
  19. Bursill D, Taylor WJ, Terkeltaub R, et al. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout. Ann Rheum Dis. 2019;78(11):1592-600. PubMed
  20. Sivera F, Andres M, Carmona L, et al. Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad panel of rheumatologists in the 3e initiative. Ann Rheum Dis 2013. pmid: 23868909 PubMed
  21. Vinik O, Wechalekar MD, Falzon L, et al. Treatment of asymptomatic hyperuricemia for the prevention of gouty arthritis, renal disease, and cardiovascular events: a systematic literature review. J Rheumatol Suppl. 2014;92:70-4. pmid: 23024028 PubMed
  22. Juraschek SP, Gelber AC, Choi HK. Effects of the Dietary Approaches to Stop Hypertension (DASH) Diet and Sodium Intake on Serum Uric Acid. Arthritis Rheumatol 2016; 68: 3002-9. pmid:27523583 PubMed
  23. Khanna D, Fitzgerald JD, Khanna PP, et al; American College of Rheumatology. 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res (Hoboken) 2012;64:1431-1446. PubMed
  24. Richette P, Doherty M, Pascual E, et al. 2016 updated EULAR evidence-based recommendations for the management of gout. Ann Rheum Dis. 2016. PMID: 27457514 PubMed
  25. Neoqi T, Chen C, Niu J et al. Alcohol quantity and type on risk of recurrent gout attacks: An internet-based case-crossover study. Am J Med, published online 21 January 2014. pmid: 24440541 PubMed
  26. Terkeltaub RA, Furst DE, Bennett K, et al. High versus low dosing of oral colchicine for early acute gout flare: twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum. 2010;62(4):1060–1068. PMID: 20131255. PubMed
  27. Zhang S, Zhang Y, Liu P, et al. Efficacy and safety of etoricoxib compared with NSAIDs in acute gout: a systematic review and a meta-analysis. Clin Rheumatol. 2016 Jan;35(1):151-8. Epub 2015 Jun 24. pmid: 26099603 PubMed
  28. Billy CA;Lim RT;Ruospo M;Palmer SC;Strippoli GFM. Corticosteroid or Nonsteroidal Antiinflammatory Drugs for the Treatment of Acute Gout: A Systematic Review of Randomized Controlled Trials. J Rheumatol. 2017 Aug 1. pii: jrheum.170137. (Review) PMID: 28765243 PubMed
  29. Rainer TH, Cheng CH, Janssens HJ, et al. Oral prednisolone in the treatment of acute gout: A pragmatic, multicenter, double-blind, randomized trial. Ann Intern Med 2016. pmid: 26903390 PubMed
  30. Zhang YK, Yang H, Zhang JY, et al. Comparison of intramuscular compound betamethasone and oral diclofenac sodium in the treatment of acute attacks of gout. Int J Clin Pract. 2014 Jan 29. pmid: 24472084 PubMed
  31. Dalbeth N, Merriman TR, Stamp LK.Gout.Lancet. 2016 Oct 22;388(10055):2039-2052. Epub 2016 Apr 21.PMID:27112094. PubMed
  32. Liew JW, Gardner GC. Use of Anakinra in Hospitalized Patients with Crystal-associated Arthritis. J Rheumatol 2019; 46: 1345-9. pmid:30647192 PubMed
  33. McCormick N, Yokose C, Wei J, et al. Comparative Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations : A General Population Cohort Study. Ann Intern Med. 2023 Jul 25. doi: 10.7326/M23-0724. Epub ahead of print. PMID: 37487215. PubMed
  34. Richette P, Doherty M, Pascual E, et al. 2016 updated EULAR evidence-based recommendations for the management of gout. Ann Rheum Dis. 2017 Jan;76(1):29-42. doi: 10.1136/annrheumdis-2016-209707. Epub 2016 Jul 25. PMID: 27457514. PubMed
  35. Kiltz U, Smolen J, Bardin T, et al. Treat-to-target (T2T) recommendations for gout. Ann Rheum Dis 2016. pmid:27658678 PubMed
  36. Taylor TH, Mecchella JN, Larson RJ et al. Initiation of allopurinol at first medical contact for acute attacks of gout: a randomized clinical trial. Am J Med 2012; 125: 1126-34. pmid:23098865 PubMed
  37. Seth R, Kydd AS, Buchbinder R, et al. Allopurinol for chronic gout. Cochrane Database Syst Rev. 2014 Oct 14;10. pmid: 25314636 PubMed
  38. Stamp LK, Taylor WJ, Jones PB et al. Starting dose is a risk factor for allopurinol hypersensitivity syndrome: A proposed safe starting dose of allopurinol. Arthritis Rheum 2012; 64: 2529-36. PubMed
  39. Tien YY, Shih MC, Tien CP, Huang HK, Tu YK. To Treat or Not to Treat? Effect of Urate-Lowering Therapy on Renal Function, Blood Pressure and Safety in Patients with Asymptomatic Hyperuricemia: A Systematic Review and Network Meta-Analysis. J Am Board Fam Med. 2022;35(1):140-151. PubMed
  40. Voelker R. Another Warning for Febuxostat. JAMA. 2019;321(13):1245. doi:10.1001/jama.2019.3043 DOI
  41. White WB, Saag KG, Becker MA, et al. Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout. N Engl J Med 2018;378(13):1200-10. New England Journal of Medicine
  42. O'Dell JR, Brophy MT, Pillinger MH, et al. Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management. N Engl J Med 2022. doi:10.1056/EVIDoa2100028 DOI
  43. MacKenzie IS, Ford I, Nuki G, et al. Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet 2020. pmid:33181081 PubMed
  44. Lim SY, Lu N, Choi HK. Septic arthritis in gout patients: a population-based cohort study. Rheumatology (Oxford) 2015; 54: 2095-9. PMID: 26170377 PubMed
  45. Hong J-Y, Lan T-Y, Tang G-J, et al. Gout and the risk of dementia. Arthritis Res Ther 2015;17: 139. PMID: 26018424. PubMed
  46. Shahin L, Patel KM, Heydari MK, Kesselman MM. Hyperuricemia and Cardiovascular Risk. Cureus. 2021;13(5):e14855. Published 2021 May 5. PMID: 34104597 PubMed
  47. Huang W-S, Lin C-L, Tsai C-H, Chang K-H. Association of gout with CAD and effect of antigout therapy on CVD risk among gout patients. J Inestig Med 2020; 68: 972-9. pmid:32098832 PubMed
  48. Chen J-H, Lan J-L, Cheng C-F, et al. Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study. J Rheumatol 2015; 42: 1694-1701. pmid: 26077411 PubMed
  49. Sultan AA, Muller S, Whittle R et al. Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. CMAJ 2019; 191: E597-E603. pmid:31160496 PubMed
  50. Cipolletta E, Tata LJ, Nakafero G, Avery AJ, Mamas MA, Abhishek A. Association Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout. JAMA. 2022 Aug 2;328(5):440-450. PMID: 35916846. PubMed
  51. Uhlig T, Karoliussen LF, Sexton J, Borgen T, Haavardsholm EA, Kvien TK, Hammer HB. 12-month results from the real-life observational treat-to-target and tight-control therapy NOR-Gout study: achievements of the urate target levels and predictors of obtaining this target. RMD Open. 2021 Mar;7(1):e001628. PMID: 33782189. PubMed
  52. Doherty M, Jenkins W, Richardson H, et al. Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial. Lancet. 2018 Oct 20;392(10156):1403-1412. PMID: 30343856. PubMed
  53. Uhlig T, Karoliussen LF, Sexton J, Kvien TK, Haavardsholm EA, Perez-Ruiz F, Hammer HB. One- and 2-year flare rates after treat-to-target and tight-control therapy of gout: results from the NOR-Gout study. Arthritis Res Ther. 2022 Apr 20;24(1):88. PMID: 35443675.
  54. Singh JA, Uhlig T. Chasing crystals out of the body: will treat to serum urate target for gout help us get there?. Ann Rheum Dis 2017; 76: 629-31. pmid:28031165 PubMed
  55. Dalbeth N, Stamp L. Hyperuricaemia and gout: time for a new staging system?. Ann Rheum Dis 2014; 73: 1598-600. pmid:24718961 PubMed
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