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Covid-19, langvarige symptomer

Langvarige symptomer etter covid-19, eller "long covid" , kan blant annet være tretthet, hodepine, redusert hukommelse og konsentrasjon. De fleste som gjennomgår covid-19, får ikke langvarige symptomer.

Sist oppdatert:

3. feb. 2023

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Covid-19, senfølger . Referanselisten for dette dokumentet vises nedenfor

  1. Greenhalgh T, Sivan M, Delaney B, Evans R, Milne R. Long covid-an update for primary care. BMJ. 2022 Sep 22;378:e072117. PMID: 36137612.
  2. Folkehelseinstituttet. Senfølger etter covid-19 og nyoppstått sykdom etter covid-19. Hurtigoversikt 2022 (ny versjon). ISBN elektronisk: 978-82-8406-347-8. Publisert 15.02.2022. www.fhi.no
  3. Koronavirus - fakta, råd og tiltak. Senfølger etter covid-19 ("long covid"). Folkehelseinstituttet, sist oppdatert 20.12.2022. www.fhi.no
  4. Helsedirektoratet. Koronavirus - beslutninger og anbefalinger. Senfølger og rehabilitering etter covid-19. Sist oppdatert 09.01.2022. Siden besøkt 30.01.2023 www.helsedirektoratet.no
  5. WHO. A clinical case definition of post COVID-19condition by a Delphi consensus. World Health Organization, 2019. Last updated Oct 2021. Accessed Feb 2022 www.who.int
  6. WHO. A clinical case definition for post covid-19 condition in children and adolescents by expert consensus. World Health Organization; 16 February 2023. www.who.int
  7. National Institute for Health and Care Excellence (NICE). COVID-19 rapid guideline: managing the long-term effects of COVID-19. NICE guideline [NG188]. Published date: 18 December 2020. Last updated: 11 Nov 2021. Accessed: 30 Jan 2023 www.nice.org.uk
  8. Magnusson K, Kristoffersen DT, Dell'Isola A et al. Post-covid medical complaints following infection with SARS-CoV-2 Omicron vs Delta variants. Nat Commun. 2022 Nov 30;13(1):7363. PMID: 36450749 PubMed
  9. Skyrud K, Telle K, Magnusson K. Impacts of COVID-19 on long-term health and health care use. Preprint. 2021. doi:https://doi.org/10.1101/2021.02.16.21251807
  10. COVID Symptom Study. How long does COVID-19 last? Kings College London, 2020. https://covid19.joinzoe.com/post/covid-long-term?fbclid=IwAR1RxIcmmdL-EFjh_aI-
  11. Global Burden of Disease Long COVID Collaborators. Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021. JAMA 2022; 328: 1604-1615. pmid:36215063 PubMed
  12. Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol. 2023 Jan 13:1–14. Epub ahead of print. PMID: 36639608 PubMed
  13. Wise J. Covid-19: Two million people in the UK are estimated to be experiencing long covid, says ONS BMJ 2022; 377 :o1391 doi:10.1136/bmj.o1391 DOI
  14. Antonelli M, Pujol JC, Spector TD et al. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Lancet. 2022 Jun 18;399(10343):2263-2264. PMID: 35717982 PubMed
  15. Sudre CH, Murray B, Varsavsky T. Attributes and predictors of long COVID. Nat Med (2021). https://doi.org/10.1038/s41591-021-01292-y
  16. Torres-Castro R, Vasconcello-Castillo L, Alsina-Restoy X et al. Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis. Pulmonology. 2020 Nov 25:S2531-0437(20)30245-2. Epub ahead of print. PMID: 33262076 PubMed
  17. Al-Aly Z, Xie Y and Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature (2021). https://doi.org/10.1038/s41586-021-03553-9. PMID: 33887749 PubMed
  18. Lindholm E, Tønnessen TI. Prolonged illness after COVID-19 published correction appears in Tidsskr Nor Laegeforen. 2020 Oct 19;140(16):. Langvarig syk etter covid-19 published correction appears in Tidsskr Nor Laegeforen. 2020 Oct 19;140(16):. Tidsskr Nor Laegeforen. 2020;140(14):10.4045/tidsskr.20.0753. Published 2020 Sep 29. doi:10.4045/tidsskr.20.0753 DOI
  19. Selvakumar J, Havdal LB, Drevvatne M, et al. Prevalence and Characteristics Associated With Post–COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults. JAMA Netw Open. 2023;6(3):e235763. doi:10.1001/jamanetworkopen.2023.5763 DOI
  20. Sykes DL, Holdsworth L, Jawad N et al. Post-COVID-19 Symptom Burden: What is Long-COVID and How Should We Manage It? Lung. 2021 Apr;199(2):113-119. Epub 2021 Feb 11. PMID: 33569660 PubMed
  21. Pretorius E, Vlok M, Venter C, et al. Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovasc Diabetol. 2021;20(1):172. Published 2021 Aug 23. doi:10.1186/s12933-021-01359-7 DOI
  22. Cervia-Hasler C, Brüningk SH, Hoch T, et al. Persistent complement dysregulation with signs of thromboinflammation in active Long Covid. Science 2024. pmid:38236961 PubMed
  23. Tsampasian V, Elghazaly H, Chattopadhyay R, et al. Risk factors associated with post−COVID-19 condition: A systematic review and meta-analysis. JAMA Intern Med 2023. PMID: 36951832 PubMed
  24. Davis HE, Assaf GS, McCorkell L, et al. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact published online ahead of print, 2021 Jul 15. EClinicalMedicine. 2021;101019. doi:10.1016/j.eclinm.2021.101019 DOI
  25. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, et al.. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Sci Rep. 2021 Aug 9;11(1):16144. PMID: 34373540 PubMed
  26. Himmels JPW, Qureshi SA, Brurberg KG, Gravningen KM. COVID-19: LongTerm Effects of COVID-19 [Langvarige effekter av covid-19. Hurtigoversikt 2021] Oslo: Norwegian Institute of Public Health, 2021 legehandboka.no
  27. SBU. Långvariga symtom vid covid-19. PUBLIKATIONSTYP: SBU BEREDER. Rapport 319. Publicerad 20-12-21. Hämtad 21-05-25.
  28. Iqbal FM, Lam K, Sounderajah V et al. Characteristics and predictors of acute and chronic post-COVID syndrome: A systematic review and meta-analysis. EClinicalMedicine. 2021 May 24;36:100899. PMID: 34036253 PubMed
  29. Walker A, Pottinger G, Scott A, Hopkins C. Anosmia and loss of smell in the era of covid-19. BMJ. 2020;370:m2808. Published 2020 Jul 21. Pmid: 32694187 PubMed
  30. Johansson M, Ståhlberg M, Runold M, et al. Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrome: The Swedish Experience. JACC Case Rep. 2021;3(4):573-580. doi:10.1016/j.jaccas.2021.01.009 DOI
  31. Espinosa-Gonzalez AB, Master H, Gall N et al. Orthostatic tachycardia after covid-19. BMJ. 2023 Feb 24;380:e073488. Erratum in: BMJ. 2023 Mar 21;380:p675. PMID: 36828559 PubMed
  32. Kalin A, Javid B, Knight M et al. Direct and indirect evidence of efficacy and safety of rapid exercise tests for exertional desaturation in Covid-19: a rapid systematic review. Syst Rev. 2021 Mar 16;10(1):77. PMID: 33726854 PubMed
  33. Abbasi J. The COVID Heart—One Year After SARS-CoV-2 Infection, Patients Have an Array of Increased Cardiovascular Risks. JAMA 2022; 327: 1113-1114. doi:10.1001/jama.2022.2411 DOI
  34. Greenhalgh T, Knight M, A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary care. BMJ. 2020;370:m3026. Published 2020 Aug 11. PMID: 32784198 PubMed
  35. Lu Y, Li P, Li N et al. Effects of Home-Based Breathing Exercises in Subjects With COPD. Respir Care. 2020 Mar;65(3):377-387. doi: 10.4187/respcare.07121. Epub 2019 Nov 12. PMID: 31719191.
  36. Sorokowska A, Drechsler E, Karwowski M, Hummel T. Effects of olfactory training: a meta-analysis. Rhinology. 2017 Mar 1;55(1):17-26. PMID: 28040824.
  37. Hopkins C, Alanin M, Philpott C et al. Management of new onset loss of sense of smell during the COVID-19 pandemic - BRS Consensus Guidelines. Clin Otolaryngol. 2021 Jan;46(1):16-22. Epub 2020 Sep 24. PMID: 32854169 PubMed
  38. Khan AM, Piccirillo J, Kallogjeri D, Piccirillo JF. Efficacy of Combined Visual-Olfactory Training With Patient-Preferred Scents as Treatment for Patients With COVID-19 Resultant Olfactory Loss: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2022 Dec 29. Epub ahead of print. PMID: 36580304 PubMed
  39. Sunnaas sykehus. Covid-19 rehabilitering. Sist oppdatert 16.12.2022. Siden besøkt 30.01.2023 www.sunnaas.no
  40. McGregor G, Sandhu H, Bruce J, et al. Clinical effectiveness of an online supervised group physical and mental health rehabilitation programme for adults with post-covid-19 condition (REGAIN study): multicentre randomised controlled trial. BMJ 2024; 384: e076506. pmid:38325873 PubMed
  41. Lundberg-Morris L, Leach S, Xu Y, et al. Covid-19 vaccine effectiveness against post-covid-19 condition among 589 722 individuals in Sweden: population based cohort study. BMJ 2023; 383: e076990. pmid:37993131 PubMed
  42. Xie Y, Choi T, Al-Aly Z. Association of Treatment With Nirmatrelvir and the Risk of Post–COVID-19 Condition. JAMA Intern Med 2023. pmid:36951829 PubMed
  43. Skyrud KD, Hernæs KH, Telle KE, Magnusson K. Impacts of mild COVID-19 on elevated use of primary and specialist health care services: A nationwide register study from Norway. PLoS One. 2021 Oct 8;16(10):e0257926. PMID: 34624023 PubMed
  44. Blomberg B, Mohn KG, Brokstad KA, et al. Long COVID in a prospective cohort of home-isolated patients. Nat Med. 2021;27(9):1607-1613. doi:10.1038/s41591-021-01433-3 DOI
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