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Gallesteinsykdom

Gallestein dannes i galleblæra. Hos 80 prosent medfører dette ingen problemer, men for de resterende kan det føre til gallesteinsanfall og komplikasjoner som betennelse i galleblæra.

Gallestein kan gi anfall av milde til kraftige smerter i øvre høyre del av magen, eventuelt med utstråling til ryggen og gjerne opp til høyre skulder.

Sist oppdatert:

1. juni 2023

Dette dokumentet er basert på det profesjonelle dokumentet Gallesteinsykdom . Referanselisten for dette dokumentet vises nedenfor

  1. European Association for the Study of the Liver (EASL). EASL clinical practice guidelines on the prevention, diagnosis and treatment of gallstones. J Hepatol. 2016 Jul;65(1):146-81. PubMed
  2. Shaffer E. Cholelithiasis. BMJ Best Practice, last updated 28 Oct 2020. bestpractice.bmj.com
  3. Haldestam I, Kullman E, Borch K. Incidence and potential risk factors for gallstone disease in a generla population sample. Br J Surg 2009; 96: 1315-22. PubMed
  4. Wittenburg H. Hereditary liver disease: gallstones. Best Pract Res Clin Gastroenterol. 2010;24(5):747–756.
  5. Portincasa P, Ciaula AD, Bonfrate L, Wang DQ. Therapy of gallstone disease: what it was, what it is, what it will be. World J Gastrointest Pharmacol Ther. 2012;3(2):7–20.
  6. Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver 2012;6:172-187. PubMed
  7. Sun H, Tang H, Jiang S, et al. Gender and metabolic differences of gallstone diseases. World J Gastroenterol 2009;15:1886-1891. PubMed
  8. Shabanzadeh DM, Sørensen LT, Jørgensen T. Determinants for gallstone formation - a new data cohort study and a systematic review with meta-analysis. Scand J Gastroenterol 2016. pmid: 27232657 PubMed
  9. Ross M, Brown M, McLaughlin K, et al. Emergency physician-performed ultrasound to diagnose cholelithiasis: a systematic review. Acad Emerg Med 2011;18:227-235. PubMed
  10. Samuelsen PJ, Nordmo E. Valg av opioid for akutte, sterke smerter på legevakt. Utposten 2012; 1: 38-9. PubMed
  11. Bisgaard T, Klarlund Pedersen B, Zenius Jespersen, N. Galdestenssygdom. Lægehåndbogen, sist faglig oppdatert 24.10.2022.
  12. Shabanzadeh DM, Christensen DW, Ewertsen C, et al. National clinical practice guidelines for the treatment of symptomatic gallstone disease: 2021 recommendations from the Danish Surgical Society. Scand J Surg 2022;111: 11-30. PubMed
  13. Larsen SS, Schulze S, Bisgaard T, Non-radiographic intraoperative fluorescent cholangiography is feasible. Dan Med J 2014;61: A4891 PubMed
  14. Dasari BV, Tan CJ, Gurusamy KS, et al. Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev. 2013 Dec 12;(12):CD003327. Cochrane (DOI)
  15. Helsedirektoratet. Antibiotika i sykehus. Nasjonal faglig retningslinje for bruk av antibiotika i sykehus. Sist oppdatert: 01.03.2022. helsedirektoratet.no
  16. Tazuma S, Unno M, Igarashi Y, et al. Evidence-based clinical practice guidelines for cholelithiasis 2016. J Gastroenterol. 2017 Mar. 52 (3):276-300.
  17. Zakko SF, Chopra S, Grover S. Nonsurgical treatment of gallstones. UpToDate, last updated Sep 06, 2017. www.uptodate.com
  18. Nielsen LB, Harboe KM, Bardram L, Cholecystectomy for the elderly: no hesitation for otherwise healthy patients.. Surg Endosc 2014;28: 171-7. PubMed
  19. Schmidt M, Dumot JA, Søreide O et al. Diagnosis and management of gallbladder calculus disease. Scand J Gastroenterol. 2012; 47:1257-65. PubMed
  20. Semenisina G, Rosenberg J, Gögenur I. Laparoskopisk subtotal kolecystektomi ved kompliceret galdestenssygdom. Ugeskr Læger 2010; 172: 2168. Ugeskrift for Læger
  21. Aspevik RK, Irtun Ø. Plager før og etter kolecystektomi. Tidsskr Nor Lægeforen 2005; 125: 1333-5. PubMed
  22. Bisgaard T. Sygemelding og rekonvalescens efter laparoskopisk kolecystektomi?. Ugeskr Læger 2005; 167: 2627-9. PubMed
  23. Gurusamy KS, Davidson C, Gluud C, et al. Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis. Cochrane Database Syst Rev. 2013 Jun 30;(6):CD005440. Cochrane (DOI)
  24. Feo CV, Sortini D, Ragazzi R, De Palma M, Liboni A. Randomized clinical trial of the effect of preoperative dexamethasone on nausea and vomiting after laparoscopic cholecystectomy. Br J Surg 2006; 93: 295-9. PubMed
  25. Bisgaard T. Smertebehandling ved laparoskopisk kolecystektomi. Ugeskr Læger 2005; 167: 2629-32. PubMed
  26. Vege SS. Management of acute pancreatitis. UpToDate, last updated Mar 09, 2020. UpToDate
  27. Ainsworth AP, Svendsen LB, Rutinemæssig endoskopisk retrograd kolangiopankreatikografi kan ikke anbefales ved galdestenspankreatitis. Ugeskrift for Læger 2009;171: 2566-8 PubMed
  28. Bodmer M, Brauchli YB, Krähenbühl S, Jick SS, Meier CR. Statin use and risk of gallstone disease followed by cholecystectomy. JAMA 2009; 302: 2001-7. PubMed
  29. Haal S, Guman MSS, Boerlage TCC et al. Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery (UPGRADE): a multicentre, double-blind, randomised, placebo-controlled superiority trial. Lancet Gastroenterol Hepatol. 2021 Dec;6(12):993-1001. Epub 2021 Oct 27. PMID: 34715031. PubMed
  30. Shabanzadeh DM, Sørensen LT, Jørgensen T. A prediction rule for risk stratification of incidentally discovered gallstones: Results from a large cohort study. Gastroenterology 2016; 150:156-67. PMID: 26375367 PubMed
  31. Brazzelli M, Cruickshank M, Kilonzo M, et al. Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation. Health Technol Assess. 2014 ;18(55):1-101, v-vi. doi: 10.3310/hta18550 DOI
  32. Bahram M, Gaballa G. The value of pre-operative magnetic resonance cholangiopancreatography (MRCP) in management of patients with gall stones. Int J Surg 2010;8:342-345. PubMed
  33. Abraham S, Rivero HG, Erlikh IV, et al. Surgical and nonsurgical management of gallstones. Am Fam Physician. 2014 May 15;89(10):795-802. .
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