NHI.no
Annonse
Informasjon

Blodpropp i graviditeten

Blodpropp som oppstår i benet hos gravide, starter med symptomer som kan variere fra svake til sterke smerter i låret eller i leggen. Blodpropp i lungene kan gi brått innsatte pustevansker.

Risikoen for blodpropp er fire ganger høyere hos en gravid sammenlignet med en ikke-gravid kvinne.

Sist oppdatert:

23. mars 2021

Dette dokumentet er basert på det profesjonelle dokumentet Tromboemboli under svangerskap . Referanselisten for dette dokumentet vises nedenfor

  1. Dresang LT, Fontaine P, Leeman L, King VJ. Venous thromboembolism during pregnancy. Am Fam Physician 2008; 77: 1709-16. PubMed
  2. Segal JB, Streiff MB, Hofmann LV, Thornton K, Bass EB. Management of venous thromboembolism: a systematic review for a practice guideline published correction appears in Ann Intern Med. 2007;146(5):396 Ann Intern Med 2007; 146: 211-22.
  3. Flem Jacobsen A, Sandset PM, Dahm A, Chen S, Sagberg K. Trombose, antikoagulasjon og svangerskap. Veileder i fødselshjelp, sist publisert 17. februar 2020. www.legeforeningen.no
  4. Marik PE, Plante LA. Venous thromboembolic disease and pregnancy. N Engl J Med 2008; 359:2025. New England Journal of Medicine
  5. James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol 2006; 194:1311. PubMed
  6. Bates SM, Rajasekhar A, Middeldorp S, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv. 2018;2(22):3317-3359. PubMed
  7. Hauk L. NPMS Releases Consensus Statement on Venous Thromboembolism During Pregnancy. Am Fam Physician. 2017 Mar 15;95(6):397-398. PMID: 28318204. PubMed
  8. Kamle H, Navi BB, Sriram N, et al. Risk of a thrombotic event after the 6-week postpartum period. N Engl J Med 2014. doi:10.1056/NEJMoa1311485 DOI
  9. Thrombosis and Embolism during Pregnancy and the Puerperium, Reducing the Risk (Green-top Guideline No. 37a). Royal College of Obstetricians and Gynaecologists, 2015. www.rcog.org.uk
  10. Blanco-Molina A, Trujillo-Santos J, Criado J, et al., for the RIETE Investigators. Venous thromboembolism during pregnancy or postpartum: findings from the RIETE Registry. Thromb Haemost 2007; 97: 186-90. PubMed
  11. Deneux-Tharaux C, Carmona E, Bouvier-Colle MH, Breart G. Postpartum maternal mortality and cesarean delivery. Obstet Gynecol 2006; 108: 541-8. PubMed
  12. Jacobsen AF, Skjeldestad FE, Sandset PM. Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study. J Thromb Haemost 2008; 6: 905-12. pmid:18363820 PubMed
  13. Sultan AA, West J, Grainge MJ et al. Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ 2016. pmid:27919934 PubMed
  14. Blondon M, Quon BS, Harrington LB, et al. Association between newborn birthweight and the risk of postpartum maternal venous thromboebolism: A population-based case-control study. Circulation 2015. doi:10.1161/CIRCULATIONAHA.114.012749 DOI
  15. Croles FN, Nasserinejad K, Duvekot JJ, et al. Pregnancy, thrombophilia, and the risk of a first venous thrombosis: systematic review and bayesian meta-analysis. BMJ. 2017 Oct 26;359:j4452. PMID: 29074563 PubMed
  16. Chaturvedi S, McCrae KR. Diagnosis and management of the antiphospholipid syndrome. Blood Rev. 2017 Nov;31(6):406-417. Epub 2017 Jul 30. PMID: 28784423 PubMed
  17. Robertson L, Wu O, Langhorne P, et al., for the Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006; 132: 171-96. PubMed
  18. Greer IA, Thomson AJ. Thromboembolic disease in pregnancy and the puerperium: acute management. Guidelines and Audit Committee of the Royal College of Obstetricians and Gynaecologists, 2007. Guideline no. 28. www.rcog.org.uk/resources/Public/pdf/green_top_28_thromboembolic_minorrevision.pdf. Accessed February 23, 2008.
  19. Qaseem A, Snow V, Barry P, et al., for the Joint American Academy of Family Physicians/American College of Physicians Panel on Deep Venous Thrombosis/Pulmonary Embolism. Current diagnosis of venous thromboembolism in primary care: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians. Ann Intern Med 2007; 146: 454-8. Annals of Internal Medicine
  20. Roy PM, Colombet I, Durieux P, Chatellier G, Sors H, Meyer G. Systematic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. BMJ 2005; 331: 259. British Medical Journal
  21. Stein PD, Woodard PK, Weg JG, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Am J Med 2006; 119: 1001-2. PubMed
  22. Matthews S. Short communication: imaging pulmonary embolism in pregnancy: what is the most appropriate imaging protocol? Br J Radiol 2006; 79: 441-4. British Journal of Radiology
  23. Quiroz R, Kucher N, Zou KH, et al. Clinical validity of a negative computed tomography scan in patients with suspected pulmonary embolism: a systematic review. JAMA 2005; 293: 2012-7. Journal of the American Medical Association
  24. Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. The Cochrane database of systematic reviews. 2018;2:Cd004982. Cochrane (DOI)
  25. Schwartz DR, Malhotra A, Weinberger SE. Deep vein thrombosis and pulmonary embolism in pregnancy: Treatment. UpToDate, last updated July 04, 2015 . UpToDate
  26. Hao Q, Dong BR, Yue J, Wu T, Liu GJ. Thrombolytic therapy for pulmonary embolism. Cochrane Database of Systematic Reviews 2015, Issue 9. Art. No.: CD004437. DOI: 10.1002/14651858.CD004437.pub4. DOI
  27. Sandset PM, Vandvik P (red.) Retningslinjer for antitrombotisk behandling og profylakse 2013. Norsk Selskap for Trombose og Hemostase http://www.magicapp.org/guideline/1
  28. Greer IA, Nelson-Piercy C. Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood 2005; 106: 401-7. Blood
  29. Bain E, Wilson A, Tooher R, Gates S, Davis LJ, Middleton P. Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. Cochrane Database Syst Rev, 2014; 2: CD001689 Doi: 10.1002/14651858.CD001689.pub3 DOI
  30. Mak A, Cheung MW, Cheak AA, Ho RC. Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression. Rheumatology (Oxford) 2010; 49: 281-8. PubMed
  31. Jacobsen AF, Skjeldestad FE, Sandset PM. Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium--a register-based case-control study. Am J Obstet Gynecol 2008 Feb;198(2):233-7. PubMed
  32. Quiñones JN, James DN, Stamilio DM, Cleary KL, Macones GA. Thromboprophylaxis after cesarean delivery: a decision analysis. Obstet Gynecol 2005; 106: 733-40. PubMed
Annonse
Annonse